We aimed to compare proximal femur geometry and biomechanics in postmenopausal\nwomen with osteoarthritis (OA) and/or osteoporosis (OP), using quantitative computed\ntomography (QCT). A retrospective analysis of QCT scans of the proximal femur of 175\npostmenopausal women was performed. Morphometric and densitometric data of the proximal\nfemur were used to evaluate its biomechanics. We found, 21 had a normal bone mineral density\n(BMD), 72 had osteopenia, and 81 were diagnosed with OP. Radiographic findings of hip OA were\nseen in 43.8%, 52.8%, and 39.5% of the normal BMD, osteopenic, and OP groups, respectively (p <\n0.05). OA was significantly correlated with total hip volume (r = 0.21), intertrochanteric cortical\nvolume (r = 0.25), and trochanteric trabecular volume (r = 0.20). In each densitometric group,\nsignificant differences in hip geometry and BMD were found between the OA and non-OA\nsubgroups. Hip OA and OP often coexist. In postmenopausal women, these diseases coexist in 40%\nof cases. Both OA and OP affect hip geometry and biomechanics. OA does so regardless of\ndensitometric status. Changes are mostly reflected in the cortical bone. OA leads to significant\nchanges in buckling ratio (BR) in both OP and non-OP women.
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